“Change your burned skin – change your life”

Gunning for success

Burn care and healing has been fraught with extreem pain and long crueling amounts of time to heal. Now the prayers have been answered with a gun. Until now burns have usually been treated with skin grafts, which involve taking skin sections from uninjured parts of the patient’s body, or growing sheets of skin artificially, and grafting them over the burn. The grafts can take several weeks or even months to heal, and during the recovery period patients are prone to infections because of the damage to the skin, which is the body’s first line of defense against pathogens.
Scientists have been able to regenerate skin in the laboratory for decades, but the process takes two to three weeks and the sheets of skin produced are fragile. When grafted on, blisters can form beneath it due to secretions, and can push up against the sheet and damage it. Scaring scars lives.

Enter the Skin-cell Gun

The skin sprayer works like a very high tech paint spray gun. Originally developed by Professor Joerg C. Gerlach and colleages of the Department of Surgery at the University of Pittsburg’s McGowan Institute for Regenerative Medicine.

Skin spraying have been in use  in Australia, where Dr Fiona Wood of the West Australia Burns Unit developed a method called “spray-on-skin.” Dr Wood’s method uses an aerosol system to spray on cultured skin cells.

This system also cuts healing time to days rather than weeks or months, and the technique substantially cut the death toll in the Bali bombings in 2002.

Dr Gerlach said the new method uses an electronically controlled pneumatic device that does not injure the cells, while the other skin spraying devices are hand-pumped atomizers.
In a process taking only an hour and a half in total, a biopsy is taken from the patient’s undamaged skin and then healthy stem cells are isolated from the biopsy and an aqueous solution containing the cells is sprayed on the burn.
The sprayed wound is then covered with a newly-developed dressing with tubes enmeshed within it and extending from each end. One set of tubes functions as an artery, while the second set functions as a vein. The tubes are connected to an “artificial vascular system” and provide electrolytes, antibiotics, amino acids and glucose to the wound. The dressing keeps the wound clean and sterile, and provides nutrition for the skin stem cells to encourage them to regenerate new skin.
After treatment the wound heals in just days, when it would have taken weeks to heal using traditional treatments. Dr Gerlach said patients had been treated at the Berlin Burn Center and they had regrown skin over a burned ear or an entire face in only a few days.

At the moment the technique can only be used on second-degree burns, but Dr Gerlach hopes it will later be able to tackle third-degree burns as well.
The research is funded by the US Department of Defense under the Armed Forces Institute of Regenerative Medicine (AFIRM) consortium of research institutions, which was formed in 2008 to research better treatments for wounded service personnel.
The Skin-cell Gun was shown on the National Geographic channel in the episode Explorer: How to Build a Beating Heart, which looks at the latest tissue regeneration techniques.
More information

Resources

Excerpts and Image courtesy of http://bit.ly/excILy

“Hearing loss in teens may be due to loud ipod music”

What is that you are saying?  Didn’t you hear me?

How many times do parents or teachers say this to their children? It seems there may be an organic reason for this temporary deafness.

Hearing loss among U.S. adolescents has surged, possibly, because of the level of noise coming through their earbuds on their  ipods while listening to music. Continue reading ““Hearing loss in teens may be due to loud ipod music””

“Ashwagandha helps calm nerves and improve brain funtioning”

Ashwaganda, also known as Indian Ginseng, has been used for centuries for anxiety, cognitive and neurological disorders and inflammation. It is high in antioxidants.Ashwaganda is also used therapeutically for patients with nervous exhaustion, and debility due to stress. It is also used as an immune stimulant as it has been shown to prevent brain cell degeneration from chronic stress.
For centuries, Indian and African medicine have used it an anti-inflammatory, for fever relief, and against infectious disease. Many believe ashwagandha to be effective in stimulating the immune system. It also appears to inhibit swelling and aid memory and can act as a general health tonic.

A study done in 1991 at the Department of Pharmacology, University of Texas Health Science Center indicated that extracts of ashwagandha had GABA-like activity. This may account for this herb’s anti-anxiety effects.
Ashwagandha is used in India to treat mental deficits in geriatric patients, including amnesia. Researchers from the University of Leipzig in Germany wanted to find out which neurotransmitters were influenced by ashwagandha. After injecting some of the chemicals in ashwagandha into rats, they later examined slices of their brain and found an increase in acetylcholine receptor activity. The researchers say, The drug-induced increase in acetylcholine receptor capacity might partly explain the cognition-enhancing and memory-improving effects of extracts from Withania somnifera [ashwagandha] observed in animals and humans.

A 2002 laboratory study indicated that ashwagandha stimulates the growth of axons and dendrites. A 2001 animal study showed ashwagandha had memory boosting ability. A 2000 study with rodents showed ashwagandha to have anti-anxiety and anti-depression effects. However, no clinical studies have been carried out to support its efficacy in humans.

Part of the Solanaceae or nightshade family as the tomato, Ashwaganda grows as a stout shrub that reaches a height of 170 cm (5.6 ft). Like the tomato which belongs to the same family, it bears yellow flowers and yellow-Orange to red Berry type fruit, though its fruit is berry-like in size and shape. It grows prolifically in India, Nepal, Pakistan, Sri Lanka and Bangladesh.
In Ayurveda, ashwagandha extract is considered an adaptogen or a substance that helps to normalize physiological function of the body and mind. In Ayurveda, the fresh roots are sometimes boiled in milk, prior to drying, in order to leach out undesirable constituents. The berries are used as a substitute for rennet, to coagulate milk in cheese making.
It has sedating properties, but it has been also used for sexual vitality and as an adaptogen. Some herbalists refer to ashwagandha as Indian ginseng, since it is used in ayurvedic medicine in a way similar to that ginseng is used in traditional Chinese medicine.
Seven American and four Japanese firms have filed for grant of patents on formulations containing extracts of the herb Ashwagandha.

Resources

Excerpts courtesy of   http://bit.ly/a1xUVK

Excerpts courtesy of   http://bit.ly/ayZLer

Image courtesy of   http://bit.ly/dkJ3Zi

"Remyelination of the spinal cord after injury may be a step closer"

Brain and spinal cord injuries may soon have a new treatment process that is natural and based on the individual’s own stem cells. Oligodendrocyte, precursor cells (OPCs), are  a type of cell found in the brain and nervous system that forms the coating around the nerve cells. These cells are formed during embryo formation in the ventricular zone of the neural tube (embryonic spinal cord), and the cells migrate outwards along the circumference of the tube, and then along its length. During this migration, OPCs actively seek axons around which they can wrap

their processes once they have differentiated into oligodendrocytes. Myelination, the process by which oligodendrocytes wrap their processes around nerve fibers, begins towards the end of embryonic development, and continues post-natally coating around the nerve cells.

These cells are formed during embryo formation in the ventricular zone of the neural tube (embryonic spinal cord), and the cells migrate outwards along the circumference of the tube, and then along its length. During this migration, OPCs actively seek axons around which they can wrap their processes once they have differentiated into oligodendrocytes. Myelination, the process by which oligodendrocytes wrap their processes around nerve fibers, begins towards the end of embryonic development, and continues postnatally.


Throughout their migration, these cells extend and retract filopodia-like processes to obtain cues from their surroundings. Upon coming into contact with neighboring OPCs. These hair or cilia like projections are withdrawn and then extended in the opposite direction. This seems to be a mutual repulsion mechanism which ensures that OPCs are evenly distributed along the length of the axons they will myelinate (coat). An axon is a long, slender extension of a nerve cell, or neuron, that conducts electrical impulses away from the neuron’s cell body

Oligodendrocyte precursor cells (OPCs) comprise 5% of the cells in the adult brain, where they are the most proliferative cell present. They can generate both neurons and glial cells, making them an important stem cell population in the adult brain.
The bottom line is that this animal model with the injection of  hESC-OPCs cells has demonstrated that remyelination of the cervical injury site and the restoration of movement to the  limbs of these animals may help restore function in spinal cord injuries victims in the future.
Resources

Excerpts courtesy of    http://bit.ly/ctDR8x
Excerpts courtesy of    http://bit.ly/cNOulI
Image of myelination process courtesy of  http://bit.ly/c8wmkH
Image of neuron courtesy of  http://bit.ly/BECvB

"Benedryl and its’ cousins maybe bad mojo for long term users"

“Researchers … conducted a six-year observational study, evaluating 1,652 Indianapolis area African-Americans over the age of 70 who had normal cognitive function when the study began … ‘[Taking one anticholinergic significantly increased an individual’s risk of developing mild cognitive impairment and taking two of these drugs doubled this risk.'” Reported in Physorg.org.

Why were elderly people allowed to take part in this study?  It disappoints and angers me.

Over the counter (OTC) drugs like Benadryl (or Dimedrol in other countries), Dramamine, Excedrin PM, Nytol, Sominex, Tylenol PM, Midol PM and Advil PM and some Unisom products if used regularly can cause decreased brain function in those over 70 years of age.  Other anticholinergic prescription drugs, such as Paxil, Detrol, Demerol and Elavil are are made with the same antihistamine Diphenhydramine like their OTC cousins.

How do these drugs work?

These drugs, called anticholinergics, block acetylcholine, a nervous system neurotransmitter. The body uses neurotransmitters to speed or slow the transmission of nerve signals throughout the brain and nervous system.

Despite Benedryl being one of the oldest antihistamines on the market it is more effective than even some of the latest prescription drugs. Consequently, it is frequently used when an allergic reaction requires fast, effective reversal of the often dangerous effects of a massive histamine release. Its active ingredient Diphenhydramine works by blocking the effect of histamine at H1 receptor sites. This results in effects such as the increase of vascular smooth muscle contraction, thus reducing the redness, hyperthermia and edema that occurs during an inflammatory reaction. In addition, by blocking the H1 receptor on peripheral nociceptors (pain receptors), diphenhydramine decreases their sensitization and thus reduces itching from an allergic reaction.

The effects of Diphenhydramine the active ingredient in many antihistamine compounds include:

  • Mouth/throat – dryness
  • Endocrine – change in appetite
  • Heart – increased heart rate (tachycardia or hypertension)
  • Liver – toxicity in very large doses
  • Brain/Memory/Nervous System –  profound drowsiness, difficulty concentrating, short-term memory loss, hallucinations, dizziness, irritability, delirium, motor impairment (ataxia), restlessness, restless leg syndrome, clouded thinking, difficult mood changes, twitching may be delayed until the drowsiness begins to cease, confusion
  • Vision-visual disturbances, abnormal sensitivity to bright light (photophobia), pupil dilation,  blurred vision at nearpoint owing to lack of accommodation (cycloplegia),  redness, dryness and yellowing of eyes
  • Respiration– irregular breathing, decreased respiration
  • Skin – itchy skin, decreased body temperature (generally in the hands and/or feet), flushing
  • Bladder/Bowel function – urinary retention, constipation, nausea, vaginal dryness,
  • Sexual -erectile dysfunction, excitability, decreased libido
  • Atypical sensations – sense of heaviness, hearing imbalances

References

Excerpts courtesy of   http://bit.ly/cmMLF7

Excerpts courtesy of  http://bit.ly/BpDrf

Image courtesy of      http://bit.ly/csdX5Y

"Communication without words after trauma or disease"

There is a new machine that can help individuals that have lost the ability to speak talk again.

Cathy Wolf  lost her ability to speak, but through a new speech assist machine called the Brain-Computer Interface system, she can communicate again.

Cathy Wolf of Katonah, N.Y., is able to manage only a small amount of muscle movement in her face and neck. Still, she’s helping test an alternative communication system that, it’s hoped, will help her and others with ALS compensate for this loss of voluntary muscle control.

Wolf currently uses the WiViK onscreen keyboard, E-triloquist speech program software and a switch she can operate with her eyebrow. When the time comes, she says, she will use BCI full time.

The Brain-Computer Interface system reads electric currents created by nerve cells talking to each other in the brain. It allows users to control a computer and communicate through e-mail, other computer-based communication systems, or synthetic speech.

Brain-Computer Interface (BCI) is under development by researchers at the Wadsworth Center, an arm of the New York State Department of Health, in Albany, N.Y. The BCI system — comprising a small laptop computer, an amplifier, a 20-inch monitor and a cap fitted with electrodes — “reads” the electric currents created by cellular activity in the brain, allowing the user to control a computer and communicate through e-mail, other computer-based communication systems or synthetic speech.

Brain signals instead of muscles It’s hoped that BCI will be made widely available for in-home use by people unable to communicate by other means as a result of disease or injury. Although it has potential for use by people affected by spinal cord injuries, stroke or other diseases, Wolf and the four other people currently testing the system all have ALS.

The BCI system is calibrated to the individual, and its use in anyone with advanced ALS requires a caregiver or someone else who can first put the cap containing the electrodes on the user’s head, and then start the system. From there, the user can control everything using brain signals instead of muscles, up to and including shutting down the computer.

In fall 1997, Wolf learned she has ALS. Since then, management of the disease has included a tracheostomy and ventilator, and a feeding tube. Unable to speak, Wolf communicates with her husband Joel and the rest of the world using a WiViK onscreen keyboard; E-triloquist speech program software; and a SCATIR switch that works through detection of a reflected beam of light and which she operates with her eyebrows.

***Compmed’s Director has been arrested****

by the MDA police.

Please help me post bail so I can continue my blogging work for you.

Arrested for a good cause. Please listen to my story and help me post bail.

All money goes to Jerry’s Kids for camp and to further research. http://bit.ly/cTzj3e

Resources

Excerpts and Image courtesy of http://bit.ly/dwk5Og

"Hope for traumatic brain injury"

“Brain injuries differ dramatically from patient to patient depending on the location, type, intensity, and duration of the injury. An injury can immediately cause rips in the white matter, brain hemorrhage, swelling, and, most commonly, bruising. One insult (i.e. hitting head, swelling, bleeding or residual trauma from an old injury to the brain)) is superimposed on another as, following the injury, the brain begins to experience reduced blood flow and oxygen deficiency…

Within minutes or hours after an injury, tiny holes rip through neuronal membranes and ion channels get stuck open, leaking proteins and neurotransmitters. Free radicals and calcium spread, causing cell death and tissue damage. Early gene activation of apoptotic enzymes sends more cells into a death spiral. Mitochondria sputter, then fall silent. Astrocytes swell. The damage can be isolated or extensive.

Researchers and doctors to date have had a very antiquated system of classification for TBIs. A new, validated system has now been devised which divides TBI patients into subgroups based on the type and location of injuries, not based on their consciousness. Then, therapies that benefit specific injury types can be targeted to those subgroups. It is the initial step toward a positive clinical trial for TBI.
Another ray of hope for the treatment of TBIs is the use of progesterone. It seems to pose the possibility of becoming the magic bullet for the treatment.
Through  Don Stein’s 27 years of research on progesterone is has been shown that progesterone  produced in the brain as well as the ovaries and can easily cross the blood brain barrier. Both men and women have progesterone receptors in their brains and it  prevents the expression of inflammatory cytokines in the brain, block apoptosis, stimulate growth-promoting factors, and even have a role in remyelination of neurons.

Thus progesterone decreases the accumulation of fluids in the brain after injury, reduces secondary neuronal loss, and improves outcomes in rats. “It’s the Swiss army knife of therapies,” laughs Douglas Smith, director of the University of Pennsylvania’s Center for Brain Injury and Repair. “It can take care of everything.”

Human trials are soon to get under way.

Natural integrated care and medicine like homeopathic remedies and acupuncture and neuro- kinesiology can be used to augment traditional care. These energetic forms of care can monitor the trauma, by the changing pulses and the meridian flows to determine how the body’s energetic systems are dealing with the trauma and then homeopathy can neural-kinesiology can de-stress the neuronal circuitry to enhance the healing and recovery process.
For more information on integrated medicine’s care of brain trauma contact.

Resources

Excerpts courtesy of       http://www.the-scientist.com
Excerpts courtesy of       http://bit.ly/bOMYrG
Image courtesy of       http://bit.ly/9fP0gH

“Potential risks of squalene in flu vaccine worse than the flu"

This frenzy over upping the number of vaccines to supposedly prevent a host of nasty diseases –at what price?

“North American children are now the most vaccinated on earth. Since 1980, Canadian vaccine schedules have more than doubled the types of vaccines given; for the first 4-6 yrs of life alone, Public Health now recommends 43 doses of thirteen different vaccines. The first 8 doses are given in four shots at two months of age. It’s been declared that today’s children are the first generation whose parents will outlive them. Why?

H1N1 virus (Swine Flu)
H1N1 virus (Swine Flu)

Today, 10% of Canadian children have life threatening afflictions. In the last 25 years, concurrent with vaccine increase, there’ve been huge declines in children’s health in many categories:

* Autism – increased over 1000 times in less than one generation;

* Juvenile Diabetes – 104% increase since 1980; * Anaphylactic Food Allergies – doubled in the last decade;

* All types of Allergies – increased nearly six times;

* Obesity – now almost 20%, 3 times the prevalence in 1980;

*Attention Deficit Disorder – now almost 10%. (1)

Dr. Sherri Tenpenny, DO in the May 1, 2006 issue of NewsWithViews.com stated, “Multiple studies published in highly reputable publications have documented that flu shots are ineffective in all ages.” Besides being ineffective the adjuvant the biochemical catalyst added to the vaccine can pose further health risks.

After the Gulf War vets returned with a cascade of immuno -reactions called Gulf War syndrome.included “arthritis, fibromyalgia, lymphadenopathy, rashes, photosensitive rashes, malar rashes, chronic fatigue, chronic headaches, abnormal body hair loss, non-healing skin lesions, aphthous ulcers, dizziness, weakness, memory loss, seizures, mood changes, neuropsychiatric problems, anti-thyroid effects, anemia, elevated ESR (erythrocyte sedimentation rate), systemic lupus erythematosus, multiple sclerosis, ALS, Raynaud’s phenomenon, Sjorgren’s syndrome, chronic diarrhea, night sweats and low-grade fever.” research has attributed these symptoms to three batches of immunizations using squalen based adjuvant.(1)

squalen adjuvant in flu vaccine
squalen adjuvant in flu vaccine

Squalene is an oil-based adjuvant compound called MF-59. The main function of the adjuvant is to supercharge the live or dead virus(s) main ingredient in the diluted vaccine to make them more potent and kick start the response to the flu in the body. Two H1N1 vaccines being developed by companies Novartis and GlaxoSmithKline are adding squalene adjuvants to boost immunogenicity and dramatically reduce the amount of viral antigen needed. This translates to much faster production of desired vaccine quantities. Novartis’s proprietary squalene adjuvant for their H1N1 vaccine is MF59. Glaxo’s is ASO3. MF59 has yet to be approved by the FDA for use in any U.S. vaccine.

Natural Squalene as an oil molecule is native to your body. It is found throughout your nervous system and brain. In fact, olive oil will bless you with natural squalene and by consuming it will build your immune system as long as you are not sensitive or allergic to it.

Why does the body go to war with injected squalene compounds?

Injection is an abnormal route of entry which incites your immune system to attack all the squalene in your body, not just the vaccine adjuvant. Squalene compounded vaccines has been fingered at a possible culprit in the post Gulf War multiple health issues that these veterans continue to suffer. Two H1N1 vaccines being developed by companies Novartis and GlaxoSmithKline are adding squalene adjuvants to boost immunogenicity and dramatically reduce the amount of viral antigen needed. This translates to much faster production of desired vaccine quantities. Novartis’s proprietary squalene adjuvant for their H1N1 vaccine is MF59. Glaxo’s is ASO3. MF59 has yet to be approved by the FDA for use in any U.S. vaccine.

Flu vaccines can also contain a number of chemical toxins, including ethylene glycol (antifreeze), formaldehyde, phenol (carbolic acid) and even antibiotics like Neomycin and streptomycin. In addition to the viruses and aluminum and squalene. Vaccinations are biochemical cocktails for supression of the native immune systems that will not is help build immunity to potentially harmful organisms that cause illness and disease.

However, your body’s immune system is already designed to do this in response to organisms that invade your body naturally. Build your immunity by eating organic healthy raw and steamed fruits and seasonal veggies, staying well hydrated, getting plenty of sleep and exercise in fresh air.

Resources
Excerpts courtesy of http://vran.org/about-vaccines/vaccine-essentials/vaccination-the-basics/
Excerpts courtesy of http://en.wikipedia.org/wiki/Immunologic_adjuvant

Excerpts courtesy of http://en.wikipedia.org/wiki/Squalene

Excerpts courtesy of http://newresearchfindingstwo.blogspot.com/2009/07/squalene.html

Image 1. the flu virus courtesy of  Biochemistryquestions.wordpress.com/some-basic-biochemistry-h1n1-virus/
Image 2. squalene courtesy of  En.wikipedia.org/wiki/Squalene

"Women develop lower viral levels than men following acute HIV-1 infection"

HIV and Women

growth of HIV virus
growth of HIV virus

Women usually develop lower viral levels than men following acute HIV-1 infection.

Women with similar viral loads. will develop AIDS faster. Why?

Research team based at the Ragon Institute of Massachusetts General Hospital (MGH), MIT and Harvard has found that a receptor molecule involved in the first-line recognition of HIV-1 responds to the virus differently in women, leading to subsequent differences in chronic T cell activation, a known predictor of disease progression. Their paper, which will be published in an upcoming issue of Nature Medicine.

Resources

Excerpts courtesy of LabSpace.net labspaces.net/98592/StudymayexplainwhyHIVprogressesfasterinwomenthaninmen

Image courtesy of   Wikimedia.com  wikimedia.org/wikipedia/commons/1/1a/HIV-budding-Color.jpg